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How to use exogenous in a sentence. An exogenous model of economic growth. The meaning of exogenous is produced by growth from superficial tissue. In a variety of contexts, exogeny or exogeneity (from greek ἔξω éxō outside and -γένεια -géneia to produce) is the fact of an action or … Originating or produced from outside a cell, tissue, or organism: Found or coming from outside something, for example a system or a persons body or mind 2. · the distinction between exogenous and endogenous factors lies in their origin relative to a specific system.