Gene Editing The Future Of Wildlife Conservation

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· complete information for ass1 gene (protein coding), argininosuccinate synthase 1, including: Geneanalytics disease-related outputs rely on the information available in malacards, the most comprehensive human disease database. · map4k4 (mitogen-activated protein kinase kinase kinase kinase 4) is a protein coding gene. · the knowledgebase automatically integrates gene-centric data from ~200 web sources, including genomic, transcriptomic, proteomic, genetic, clinical and functional information. Geneanalytics enables researchers to identify diseases related to their gene sets, and to discover disease mechanisms and specific disease markers. · wt1 is a tumor suppressor gene associated with the development of wilms tumor, from which it was named. · complete information for lpl gene (protein coding), lipoprotein lipase, including: · the was gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in was patients. · this gene encodes pyruvate carboxylase, which requires biotin and atp to catalyse the carboxylation of pyruvate to oxaloacetate. Mutations in exon 7 and 9 of wt1 have been recurrently identified in acute myeloid leukemia and associated with poorer prognosis and chemotherapy resistance. · this gene encodes a nuclear-localized e3 ubiquitin ligase. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Diseases associated with map4k4 include anus, imperforate and renal dysplasia. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. The genecards human gene database index: Function, proteins, disorders, pathways, orthologs, and expression. Genecards - the human gene compendium